Cortical plasticity catalyzed by prehabilitation enables extensive resection of brain tumors in eloquent areas

Management of Brain Tumors in Eloquent Areas

Brain tumours in eloquent areas represent a great challenge for Neurosurgeons due to its surgical resection complexity. The main goal of this chapter is the comprehensive study of perioperative work-up, diagnostic and preoperative functional techniques, microsurgical skills and intraoperative monitoring for the management of brain tumours located in eloquent areas. Integral management of brain ...

Resection of Malignant Brain Tumors in Eloquent Cortical Areas: A New Multimodal Approach Combining 5-ALA and Intraoperative Monitoring

Low-grade astrocytoma: surgical outcomes in eloquent versus non-eloquent brain areas.

A retrospective study of 81 patients with low-grade astrocytoma (LGA) comparing the efficacy of aggressive versus less aggressive surgery in eloquent and non-eloquent brain areas was conducted. Extent of surgical resection was analyzed to assess overall survival (OS) and progression- free survival (PFS). Degree of tumor resection was classified as gross total resection (GTR), subtotal resection...

Brain plasticity and tumors.

Brain plasticity is the potential of the nervous system to reshape itself during ontogeny, learning or following injuries. The first part of this article reviews the pathophysiological mechanisms underlying plasticity at different functional levels. Such plastic potential means that the anatomo-functional organization of the brain in humans, both physiological and pathological, has flexibility....

Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation.

OBJECTIVES To describe functional recovery after surgical resection of low grade gliomas (LGG) in eloquent brain areas, and discuss the mechanisms of compensation. METHODS Seventy-seven right-handed patients without deficit were operated on for a LGG invading primary and/or secondary sensorimotor and/or language areas, as shown anatomically by pre-operative MRI and intraoperatively by electri...